GFguard® glass microfiber depth filter cartridges

Clarification with depth

GFguard captures suspended particles within the glass microfiber media matrix as well as at its surface. Its depth structure supports clarification and prefiltration duties upstream of membrane filters, chromatography columns and other process equipment.

Select the retention grade and cartridge configuration according to the process fluid, particulate load, flow requirement and downstream protection objective.

Available configurations

Filter medium	Glass microfiber
Retention grades	0.6 and 1.2 µm
Nominal diameter	2.75 in (7 cm)
Nominal lengths	10, 20, 30 and 40 in (25, 50, 75 and 100 cm)
Effective filtration area	0.45 m2 per 10 in length
Connections	DOE flat-gasket and SOE 222 or 226 O-ring configurations; confirm the selected end-cap format

Materials of construction

Upstream and downstream supports	Polypropylene
Core, outer guard and end caps	Polypropylene
Sealing method	Thermal bonding
Seal options	Silicone (S), as listed in the current ordering information; confirm the selected connection configuration

Operating limits

Differential pressure at 0–38 °C	80 psi (5.5 bar)
Differential pressure at 66 °C	60 psi (4.1 bar)
Differential pressure at 82 °C	30 psi (2.1 bar)
Steam-in-place	Saturated steam at 121–135 °C for 30 minutes; confirm the permitted pressure and complete cycle in the current catalogue
Autoclave	121–135 °C for 30 minutes at 2 bar, subject to the approved configuration and procedure

A stainless-steel reinforcement ring is required for autoclave or SIP applications. Confirm the compatible end-cap configuration, operating conditions and permitted cycle count before ordering.

Typical application discussions

• Cell-culture harvest, fermentation-fluid and process-pool clarification
• Protein-containing process streams and compatible pharmaceutical solutions
• Prefiltration before membrane filtration and chromatography
• Particle reduction upstream of ultrafiltration, diafiltration and TFF systems

Selection and qualification

GFguard is a clarification and particle-reduction filter. Assess process-fluid chemistry, exposure time, temperature, sterilization conditions, extractables risk and downstream requirements for the selected configuration. Request current materials, traceability and qualification documentation for the intended application.